MADRS & SDS SCALES
Research scales used in FETZIMA® pivotal trials
Two separate scales were used in the pivotal trials to assess the efficacy of FETZIMA: the Montgomery-Asberg Depression Rating Scale (MADRS) assessed the severity of depressive symptoms (primary endpoint), and the Sheehan Disability Scale (SDS) assessed functional impairment (secondary endpoint).
Montgomery-Asberg Depression Rating Scale (MADRS)11
The physician-rated MADRS measures these 10 core
symptoms of depression
- MADRS is a widely used, physician-rated scale for assessing the severity of depressive symptoms11
- Each of the 10 symptoms on the MADRS is rated on a scale of 0-6; higher numbers denote greater severity of symptoms11